Target

Gene symbol :  
Afap1l1
NCBI gene ID :  
106877
Gene full name :  
Actin filament associated protein 1 like 1
Synonym :  
XB130

Protein function

Protein name :  
AFAP1L1 protein
Adaptor protein linking signaling molecules to actin cytoskeleton, involved in cell migration and survival pathways

Expected phenotype

Altered cell motility and signaling responses reported in functional studies

Human disease relevance

Cancer progression and metastasis

Model applications

Cancer biology, cytoskeleton and migration studies

Keywords:

actin cytoskeleton, cell migration, adaptor protein

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Afap1l1

conditional Knockout mouse

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