Ankrd27 conditional Knockout mouse

Target

Gene symbol :

Ankrd27

NCBI gene ID :

245886

Gene full name :

Ankyrin repeat domain containing 27

Synonym :

Vps54

Protein function

Protein name :

VPS54 homolog protein

Component of the GARP complex, involved in retrograde transport from endosomes to Golgi

Expected phenotype

Mutant mice show neurodegeneration and motor neuron defects

Human disease relevance

Progressive motor neuron disease, neurodegeneration

Model applications

Vesicle trafficking, neurodegeneration models

Keywords:

Golgi transport, endosome trafficking, neurons

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ankrd27

conditional Knockout mouse

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