Target

Gene symbol :  
Ap2a2
NCBI gene ID :  
11772
Gene full name :  
Adaptor related protein complex 2 alpha 2 subunit
Synonym :  
AP-2α2, Ap105

Protein function

Protein name :  
AP2A2
Mediates clathrin-dependent endocytosis of membrane proteins.

Expected phenotype

Defective receptor internalization

Human disease relevance

Implicated in neurological and immune signaling

Model applications

Endocytosis, membrane trafficking

Keywords:

Clathrin-coated vesicles, Internalization

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ap2a2

conditional Knockout mouse

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