Target

Gene symbol :  
Arcn1
NCBI gene ID :  
213827
Gene full name :  
Archain 1
Synonym :  
Copd

Protein function

Protein name :  
Coatomer subunit delta
Component of the COPI vesicle coat complex, required for Golgi to ER retrograde transport and intracellular vesicle trafficking

Expected phenotype

Mutant mice show skeletal abnormalities, craniofacial defects, impaired secretion and cellular stress

Human disease relevance

Skeletal dysplasia, growth retardation syndromes

Model applications

Vesicle trafficking, Golgi function, developmental biology

Keywords:

COPI, Golgi transport, intracellular trafficking

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Arcn1

conditional Knockout mouse

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