Target

Gene symbol :  
Arhgap30
NCBI gene ID :  
226652
Gene full name :  
Rho GTPase activating protein 30
Synonym :  
RhoGAP30

Protein function

Protein name :  
Rho GTPase-activating protein 30
Negatively regulates Rho family GTPases, modulates actin cytoskeleton dynamics and cell migration

Expected phenotype

Limited in vivo phenotype data, cellular studies indicate roles in cytoskeletal regulation

Human disease relevance

Cancer cell migration and invasion

Model applications

Cell migration, cytoskeleton signaling models

Keywords:

Rho GTPase, actin dynamics, cell motility

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Arhgap30

conditional Knockout mouse

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