Target

Gene symbol :  
Ascc3
NCBI gene ID :  
77987
Gene full name :  
Activating signal cointegrator 1 complex subunit 3
Synonym :  
Helz2

Protein function

Protein name :  
ASCC3 helicase
DNA and RNA helicase involved in transcriptional regulation and cellular stress responses

Expected phenotype

Disruption affects transcriptional stress responses and cell survival

Human disease relevance

Cancer and transcription-coupled stress disorders

Model applications

Transcription regulation, DNA repair and stress response models

Keywords:

helicase, transcription stress, DNA repair

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ascc3

conditional Knockout mouse

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