Ascc3 conditional Knockout mouse

Target

Gene symbol :

Ascc3

NCBI gene ID :

77987

Gene full name :

Activating signal cointegrator 1 complex subunit 3

Synonym :

Helz2

Protein function

Protein name :

ASCC3 helicase

DNA and RNA helicase involved in transcriptional regulation and cellular stress responses

Expected phenotype

Disruption affects transcriptional stress responses and cell survival

Human disease relevance

Cancer and transcription-coupled stress disorders

Model applications

Transcription regulation, DNA repair and stress response models

Keywords:

helicase, transcription stress, DNA repair

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ascc3

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe