Atg3 conditional Knockout mouse

Target

Gene symbol :

Atg3

NCBI gene ID :

67841

Gene full name :

Autophagy related 3

Synonym :

Apg3, Autophagy3

Protein function

Protein name :

Autophagy-related protein 3

E2-like enzyme essential for LC3 lipidation during autophagosome formation

Expected phenotype

Knockout mice show defective autophagy, neonatal lethality, accumulation of protein aggregates

Human disease relevance

Neurodegeneration, cancer, metabolic diseases

Model applications

Autophagy models, cell stress response

Keywords:

autophagy, LC3 conjugation, proteostasis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atg3

conditional Knockout mouse

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