Atg4b conditional Knockout mouse

Target

Gene symbol :

Atg4b

NCBI gene ID :

66615

Gene full name :

Autophagy related 4B cysteine peptidase

Synonym :

Apg4b, Autophagy4B

Protein function

Protein name :

Autophagy-related cysteine protease ATG4B

Processes LC3 and GABARAP proteins, required for autophagosome maturation

Expected phenotype

Disrupted autophagy flux, altered immune and neuronal homeostasis

Human disease relevance

Cancer, neurodegenerative disorders

Model applications

Autophagy and lysosomal pathway models

Keywords:

autophagosome maturation, cysteine protease

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atg4b

conditional Knockout mouse

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