Atn1 conditional Knockout mouse

Target

Gene symbol :

Atn1

NCBI gene ID :

13498

Gene full name :

Atrophin 1

Synonym :

Drpla, Atrophin1

Protein function

Protein name :

Atrophin-1 protein

Nuclear transcriptional coregulator involved in neuronal development and gene repression

Expected phenotype

Polyglutamine-expanded alleles cause progressive neurodegeneration and motor defects

Human disease relevance

Dentatorubral-pallidoluysian atrophy

Model applications

Neurodegeneration and polyglutamine disease models

Keywords:

polyglutamine, neurodegeneration, transcription

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atn1

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe