Atn1 conditional Knockout mouse

Target

Gene symbol :

Atn1

NCBI gene ID :

13498

Gene full name :

Atrophin 1

Synonym :

Drpla, Atrophin1

Protein function

Protein name :

Atrophin-1 protein

Nuclear transcriptional coregulator involved in neuronal development and gene repression

Expected phenotype

Polyglutamine-expanded alleles cause progressive neurodegeneration and motor defects

Human disease relevance

Dentatorubral-pallidoluysian atrophy

Model applications

Neurodegeneration and polyglutamine disease models

Keywords:

polyglutamine, neurodegeneration, transcription

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atn1

conditional Knockout mouse

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