Atp2a1 conditional Knockout mouse

Target

Gene symbol :

Atp2a1

NCBI gene ID :

11937

Gene full name :

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

Synonym :

SERCA1

Protein function

Protein name :

SERCA1

Pumps calcium from cytosol into the sarcoplasmic reticulum during muscle relaxation.

Expected phenotype

Impaired muscle contraction, fatigue

Human disease relevance

Linked to Brody disease and muscle disorders

Model applications

Muscle physiology, calcium cycling

Keywords:

SERCA, Calcium pump, Muscle contraction

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atp2a1

conditional Knockout mouse

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