Target

Gene symbol :  
Atp5if1
NCBI gene ID :  
11983
Gene full name :  
ATP synthase inhibitory factor subunit 1
Synonym :  
IF1, ATPIF1

Protein function

Protein name :  
ATPase inhibitory factor 1
Inhibits mitochondrial ATP synthase under low energy conditions to prevent ATP hydrolysis

Expected phenotype

Altered mitochondrial bioenergetics and ATP regulation

Human disease relevance

Mitochondrial disorders, metabolic disease

Model applications

Mitochondrial energy metabolism models

Keywords:

ATP synthase regulation, mitochondria

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Atp5if1

conditional Knockout mouse

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