Atp6v1d conditional Knockout mouse

Target

Gene symbol :

Atp6v1d

NCBI gene ID :

73834

Gene full name :

ATPase H+ transporting V1 subunit D

Synonym :

Atp6v1d1, V1D

Protein function

Protein name :

V-type proton ATPase subunit D

Subunit of the V1 domain of vacuolar ATPase, required for ATP hydrolysis and proton transport to acidify intracellular compartments

Expected phenotype

Disruption affects organelle acidification, vesicular trafficking, and cellular homeostasis

Human disease relevance

Renal disorders, bone disease, neurodevelopmental defects

Model applications

Vesicle acidification, lysosomal function models

Keywords:

V-ATPase, proton transport, lysosome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atp6v1d

conditional Knockout mouse

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