Bmp10 conditional Knockout mouse

Target

Gene symbol :

Bmp10

NCBI gene ID :

12154

Gene full name :

Bone morphogenetic protein 10

Synonym :

—

Protein function

Protein name :

Bone morphogenetic protein 10

Secreted growth factor of the TGF-beta superfamily, essential for cardiac development and growth

Expected phenotype

Knockout mice show severe cardiac developmental defects and embryonic lethality

Human disease relevance

Congenital heart disease, cardiomyopathies

Model applications

Cardiovascular development models

Keywords:

TGF-beta signaling, heart development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Bmp10

conditional Knockout mouse

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