Target

Gene symbol :  
Bphl
NCBI gene ID :  
68021
Gene full name :  
Biphenyl hydrolase like
Synonym :  
Vah

Protein function

Protein name :  
Valacyclovir hydrolase-like protein
Serine hydrolase involved in xenobiotic and prodrug metabolism, hydrolyzes ester-containing compounds

Expected phenotype

Altered drug metabolism and detoxification capacity in functional studies

Human disease relevance

Pharmacogenomics, drug metabolism variability

Model applications

Drug metabolism and toxicology models

Keywords:

xenobiotic metabolism, hydrolase, prodrug activation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Bphl

conditional Knockout mouse

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