Target

Gene symbol :  
Btnl2
NCBI gene ID :  
547431
Gene full name :  
Butyrophilin like 2
Synonym :  
BTNL2

Protein function

Protein name :  
Butyrophilin-like protein 2
Immunoregulatory molecule modulating T cell activation and immune tolerance

Expected phenotype

Altered T cell responses and immune regulation when disrupted

Human disease relevance

Sarcoidosis, autoimmune diseases

Model applications

Immunology and immune checkpoint research

Keywords:

immune regulation, T cell modulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Btnl2

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe