Cacnb4 conditional Knockout mouse

Target

Gene symbol :

Cacnb4

NCBI gene ID :

12298

Gene full name :

Calcium voltage-gated channel auxiliary subunit beta 4

Synonym :

Cchb4

Protein function

Protein name :

Voltage-dependent calcium channel beta-4 subunit

Auxiliary subunit regulating trafficking and gating of voltage-gated calcium channels

Expected phenotype

Ataxia, seizures, and motor coordination defects in mutant mice

Human disease relevance

Episodic ataxia, epilepsy

Model applications

Neurophysiology and channelopathy models

Keywords:

calcium channels, neuronal excitability

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cacnb4

conditional Knockout mouse

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