Casq1 conditional Knockout mouse

Target

Gene symbol :

Casq1

NCBI gene ID :

12372

Gene full name :

Calsequestrin 1

Synonym :

Casq

Protein function

Protein name :

Calsequestrin-1

Major calcium-binding protein of the sarcoplasmic reticulum in skeletal muscle, regulates calcium storage and release

Expected phenotype

Muscle weakness, altered excitation–contraction coupling, susceptibility to heat-induced stress

Human disease relevance

Malignant hyperthermia, muscle myopathies

Model applications

Muscle physiology and calcium signaling models

Keywords:

calcium homeostasis, skeletal muscle

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Casq1

conditional Knockout mouse

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