Cbx6 conditional Knockout mouse

Target

Gene symbol :

Cbx6

NCBI gene ID :

494448

Gene full name :

Chromobox 6

Synonym :

—

Protein function

Protein name :

Chromobox protein homolog 6

Epigenetic reader; binds methylated histones and represses gene expression via PRC1

Expected phenotype

Redundancy with other CBX proteins; few unique phenotypes in mouse

Human disease relevance

Implicated in epigenetic control in cancer and stem cells

Model applications

Used in studies of Polycomb repression and stem cell regulation

Keywords:

Polycomb, Epigenetics, Chromatin, Transcriptional repression

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cbx6

conditional Knockout mouse

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