Ccr8 conditional Knockout mouse

Target

Gene symbol :

Ccr8

NCBI gene ID :

12776

Gene full name :

C-C motif chemokine receptor 8

Synonym :

Cmkbr8, CDw198

Protein function

Protein name :

CCR8

Chemokine receptor expressed on Tregs and Th2 cells; guides immune cells to inflamed tissues.

Expected phenotype

Impaired Treg localization

Human disease relevance

Associated with asthma, inflammation, and cancer

Model applications

Treg migration, inflammatory diseases

Keywords:

Chemotaxis, Treg, Tumor microenvironment

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Ccr8

conditional Knockout mouse

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hPD-1 hLAG3

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.