Ccr8 conditional Knockout mouse

Target

Gene symbol :

Ccr8

NCBI gene ID :

12776

Gene full name :

C-C motif chemokine receptor 8

Synonym :

Cmkbr8, CDw198

Protein function

Protein name :

CCR8

Chemokine receptor expressed on Tregs and Th2 cells; guides immune cells to inflamed tissues.

Expected phenotype

Impaired Treg localization

Human disease relevance

Associated with asthma, inflammation, and cancer

Model applications

Treg migration, inflammatory diseases

Keywords:

Chemotaxis, Treg, Tumor microenvironment

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ccr8

conditional Knockout mouse

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