Target

Gene symbol :  
Cd276
NCBI gene ID :  
102657
Gene full name :  
CD276 molecule
Synonym :  
B7-H3, Cd276 antigen

Protein function

Protein name :  
CD276 protein
Immunoregulatory surface protein modulating T cell responses, acts as immune checkpoint molecule

Expected phenotype

Altered immune responses and tumor immune evasion in functional studies

Human disease relevance

Cancer immunotherapy target

Model applications

Immuno-oncology, immune checkpoint models

Keywords:

immune checkpoint, T cell regulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cd276

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe