Clk1 conditional Knockout mouse

Target

Gene symbol :

Clk1

NCBI gene ID :

12747

Gene full name :

CDC like kinase 1

Synonym :

Sty, Clk

Protein function

Protein name :

CDC-like kinase 1

Serine threonine kinase that phosphorylates SR proteins and regulates pre-mRNA splicing

Expected phenotype

Altered RNA splicing patterns, developmental and cellular growth defects in functional studies

Human disease relevance

Cancer, splicing-related disorders

Model applications

RNA splicing and transcription regulation models

Keywords:

SR protein phosphorylation, mRNA splicing

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Clk1

conditional Knockout mouse

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