Target

Gene symbol :  
Cnot6l
NCBI gene ID :  
231464
Gene full name :  
CCR4-NOT transcription complex subunit 6 like
Synonym :  
CCR4d

Protein function

Protein name :  
CCR4-NOT deadenylase subunit 6-like
Deadenylase involved in mRNA turnover and post-transcriptional gene regulation

Expected phenotype

Impaired mRNA decay, defects in germ cell and early embryonic development

Human disease relevance

Infertility, developmental disorders

Model applications

Post-transcriptional regulation, RNA metabolism models

Keywords:

mRNA deadenylation, RNA stability

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cnot6l

conditional Knockout mouse

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