Cntnap1 conditional Knockout mouse

Target

Gene symbol :

Cntnap1

NCBI gene ID :

53321

Gene full name :

Contactin associated protein 1

Synonym :

Caspr, Paranodin

Protein function

Protein name :

CASPR protein

Cell adhesion molecule essential for organization of paranodal junctions in myelinated axons

Expected phenotype

Disrupted paranodal junctions, impaired nerve conduction, severe neurological defects

Human disease relevance

Congenital hypomyelinating neuropathy

Model applications

Myelination and axon domain organization models

Keywords:

axon-glia interaction, myelination

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cntnap1

conditional Knockout mouse

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