Col4a5 conditional Knockout mouse

Target

Gene symbol :

Col4a5

NCBI gene ID :

12830

Gene full name :

Collagen type IV alpha 5 chain

Synonym :

CollagenIVa5, Alport

Protein function

Protein name :

Type IV collagen alpha-5 chain

Structural component of basement membranes, essential for kidney and inner ear integrity

Expected phenotype

Progressive kidney disease, hearing defects in mutant mice

Human disease relevance

Alport syndrome

Model applications

Renal disease and basement membrane models

Keywords:

basement membrane, collagen IV, kidney disease

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Col4a5

conditional Knockout mouse

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