Cops4 conditional Knockout mouse

Target

Gene symbol :

Cops4

NCBI gene ID :

26891

Gene full name :

COP9 signalosome subunit 4

Synonym :

CSN4

Protein function

Protein name :

COP9 signalosome subunit 4

Component of the COP9 signalosome complex, regulates protein degradation via deneddylation of cullin-RING ligases

Expected phenotype

Cell cycle defects and impaired protein homeostasis in functional studies

Human disease relevance

Cancer, proteostasis disorders

Model applications

Ubiquitin-proteasome system models

Keywords:

COP9 signalosome, protein degradation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cops4

conditional Knockout mouse

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