Csf2rb conditional Knockout mouse

Target

Gene symbol :

Csf2rb

NCBI gene ID :

12983

Gene full name :

Colony stimulating factor 2 receptor beta common subunit

Synonym :

Cd131, Csf2rb1

Protein function

Protein name :

GM-CSF receptor beta chain

Shared signal-transducing subunit for GM-CSF, IL-3, and IL-5 receptors, mediates hematopoietic cell proliferation and survival

Expected phenotype

Impaired granulocyte and macrophage development, defective immune responses

Human disease relevance

Immunodeficiency, inflammatory disorders

Model applications

Hematopoiesis and cytokine signaling models

Keywords:

cytokine receptor, myeloid cells

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Csf2rb

conditional Knockout mouse

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