Cstb conditional Knockout mouse

Target

Gene symbol :

Cstb

NCBI gene ID :

13014

Gene full name :

Cystatin B

Synonym :

Stefin B, Cystatin B

Protein function

Protein name :

Cystatin-B protein

Intracellular cysteine protease inhibitor regulating cathepsin activity and cellular homeostasis

Expected phenotype

Neurodegeneration, seizures, increased apoptosis in loss-of-function models

Human disease relevance

Progressive myoclonus epilepsy

Model applications

Neurodegeneration and protease regulation models

Keywords:

cysteine protease inhibitor, neuronal survival

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cstb

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe