Ctsd conditional Knockout mouse

Target

Gene symbol :

Ctsd

NCBI gene ID :

13033

Gene full name :

Cathepsin D

Synonym :

CatD

Protein function

Protein name :

Cathepsin D protein

Lysosomal aspartic protease essential for intracellular protein degradation and apoptosis regulation

Expected phenotype

Neurodegeneration, retinal atrophy, early postnatal lethality in null mutants

Human disease relevance

Neuronal ceroid lipofuscinosis, cancer

Model applications

Neurodegeneration and lysosomal biology models

Keywords:

lysosome, aspartic protease

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ctsd

conditional Knockout mouse

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