Cyba conditional Knockout mouse

Target

Gene symbol :

Cyba

NCBI gene ID :

13057

Gene full name :

Cytochrome b-245 alpha chain

Synonym :

b558, nmf333, p22phox, p22-phox

Protein function

Protein name :

NADPH oxidase subunit p22phox

Essential subunit of NADPH oxidase complexes required for reactive oxygen species generation

Expected phenotype

Impaired oxidative burst and defective innate immune responses in knockout mice

Human disease relevance

Chronic granulomatous disease and inflammatory phenotypes

Model applications

Model for oxidative stress and innate immunity

Keywords:

NADPH oxidase, ROS, Innate immunity, Inflammation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cyba

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe