Cyp19a1 conditional Knockout mouse

Target

Gene symbol :

Cyp19a1

NCBI gene ID :

13075

Gene full name :

Cytochrome P450 family 19 subfamily A member 1

Synonym :

Aromatase, Cyp19

Protein function

Protein name :

Aromatase

Catalyzes conversion of androgens to estrogens, essential for estrogen biosynthesis

Expected phenotype

Defective sexual development, infertility, altered bone and metabolic phenotypes

Human disease relevance

Aromatase deficiency, hormone-dependent cancers

Model applications

Endocrinology and reproductive biology models

Keywords:

estrogen biosynthesis, steroid metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cyp19a1

conditional Knockout mouse

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