Ddr1 conditional Knockout mouse

Target

Gene symbol :

Ddr1

NCBI gene ID :

12305

Gene full name :

Discoidin domain receptor family member 1

Synonym :

Cak, Nep, PTK3A, CD167a, 6030432F18

Protein function

Protein name :

Discoidin domain-containing receptor 1

Collagen-activated receptor tyrosine kinase regulating cell adhesion migration and extracellular matrix signaling

Expected phenotype

Altered tissue remodeling including kidney mammary gland and immune phenotypes

Human disease relevance

Fibrosis and cancer progression

Model applications

Model for collagen signaling and fibrosis

Keywords:

Collagen receptor, RTK, ECM signaling, Fibrosis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ddr1

conditional Knockout mouse

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