Target

Gene symbol :  
Ddx43
NCBI gene ID :  
100048658
Gene full name :  
DEAD-box helicase 43
Synonym :  
HAGE

Protein function

Protein name :  
ATP-dependent RNA helicase DDX43
RNA helicase involved in RNA processing and translational regulation, normally low expression with activation in specific cell states

Expected phenotype

Limited mouse phenotype data, expression induced in proliferative contexts

Human disease relevance

Cancer testis antigen, tumor progression

Model applications

Cancer biology, RNA metabolism models

Keywords:

RNA helicase, translational control

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ddx43

conditional Knockout mouse

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