Dennd1b conditional Knockout mouse

Target

Gene symbol :

Dennd1b

NCBI gene ID :

329260

Gene full name :

DENN domain containing 1B

Synonym :

FAM31B

Protein function

Protein name :

DENN domain-containing protein 1B

Guanine nucleotide exchange factor (GEF) for Rab35; regulates endocytosis and T cell function

Expected phenotype

Immune response alterations in KO models

Human disease relevance

Linked to asthma and inflammatory disorders

Model applications

Model for T cell signaling and immune regulation

Keywords:

Rab GTPase, Endocytosis, Immunity, T cells, Asthma

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dennd1b

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe