Target

Gene symbol :  
Diaph2
NCBI gene ID :  
54004
Gene full name :  
Diaphanous related formin 2
Synonym :  
Dia2, mDia2

Protein function

Protein name :  
Diaphanous-related formin 2
Actin nucleation factor regulating cytoskeleton dynamics, cell migration, and cytokinesis

Expected phenotype

Defects in cytoskeletal organization and cell division in functional models

Human disease relevance

Ovarian failure, cancer cell invasion

Model applications

Cytoskeleton and cell migration models

Keywords:

actin polymerization, formin

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Diaph2

conditional Knockout mouse

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