Dse conditional Knockout mouse

Target

Gene symbol :

Dse

NCBI gene ID :

212898

Gene full name :

Dermatan sulfate epimerase

Synonym :

Glce2, DS-epi2

Protein function

Protein name :

Dermatan sulfate epimerase 2

Catalyzes epimerization of glucuronic acid to iduronic acid during dermatan sulfate biosynthesis

Expected phenotype

Altered extracellular matrix composition, connective tissue abnormalities

Human disease relevance

Musculocontractural Ehlers-Danlos syndrome

Model applications

Connective tissue and ECM biology models

Keywords:

dermatan sulfate, extracellular matrix

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dse

conditional Knockout mouse

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