Dusp4 conditional Knockout mouse

Target

Gene symbol :

Dusp4

NCBI gene ID :

319520

Gene full name :

Dual specificity phosphatase 4

Synonym :

MKP-2, PAC-1

Protein function

Protein name :

Dual specificity protein phosphatase 4

Deactivates MAPKs (ERK, JNK); regulates cell proliferation and immune responses

Expected phenotype

KO mice show altered cytokine production and T cell responses

Human disease relevance

Implicated in cancer, immune regulation, and inflammation

Model applications

Used in MAPK pathway and immune modulation studies

Keywords:

MAPK, DUSP, Immune regulation, Inflammation, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dusp4

conditional Knockout mouse

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