Ect2 conditional Knockout mouse

Target

Gene symbol :

Ect2

NCBI gene ID :

13605

Gene full name :

Epithelial cell transforming 2

Synonym :

Pbl

Protein function

Protein name :

ECT2 protein

Rho guanine nucleotide exchange factor controlling cytokinesis and cell cycle progression

Expected phenotype

Cytokinesis failure, embryonic lethality, genomic instability in loss-of-function models

Human disease relevance

Cancer, chromosomal instability disorders

Model applications

Cell cycle and cytokinesis models

Keywords:

Rho GTPase, cytokinesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ect2

conditional Knockout mouse

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