Egfr conditional Knockout mouse

Target

Gene symbol :

Egfr

NCBI gene ID :

13649

Gene full name :

Epidermal growth factor receptor

Synonym :

Erbb1, Egfr1

Protein function

Protein name :

Epidermal growth factor receptor

Receptor tyrosine kinase regulating cell proliferation, survival, and differentiation

Expected phenotype

Defective epithelial development, impaired organogenesis, perinatal lethality in null mutants

Human disease relevance

Cancer, developmental disorders

Model applications

Growth factor signaling and oncology models

Keywords:

receptor tyrosine kinase, EGFR signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Egfr

conditional Knockout mouse

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