Elmod1 conditional Knockout mouse

Target

Gene symbol :

Elmod1

NCBI gene ID :

270162

Gene full name :

ELMO domain containing 1

Synonym :

—

Protein function

Protein name :

Engulfment and motility domain-containing protein 1

GTPase-activating protein (GAP) for ARF family; involved in actin cytoskeleton remodeling

Expected phenotype

KO leads to deafness due to stereocilia defects

Human disease relevance

Associated with sensorineural hearing loss

Model applications

Model for auditory function and hair cell biology

Keywords:

ARF-GAP, Hearing loss, Actin cytoskeleton, Stereocilia

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Elmod1

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe