Target

Gene symbol :  
Elovl4
NCBI gene ID :  
83603
Gene full name :  
ELOVL fatty acid elongase 4
Synonym :  
Bald

Protein function

Protein name :  
Elongation of very long chain fatty acids protein 4
Catalyzes elongation of very long chain fatty acids, critical for retina and skin barrier lipid synthesis

Expected phenotype

Retinal degeneration, skin barrier defects, perinatal lethality in severe alleles

Human disease relevance

Stargardt-like macular dystrophy, ichthyosis

Model applications

Retinal disease and lipid metabolism models

Keywords:

very long chain fatty acids, retina

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Elovl4

conditional Knockout mouse

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