Ephx1 conditional Knockout mouse

Target

Gene symbol :

Ephx1

NCBI gene ID :

13849

Gene full name :

Epoxide hydrolase 1

Synonym :

mEH, Epxh

Protein function

Protein name :

Microsomal epoxide hydrolase

Detoxifies epoxides derived from xenobiotics and endogenous compounds

Expected phenotype

Altered xenobiotic metabolism and increased susceptibility to toxic insults

Human disease relevance

Cancer susceptibility, toxicology

Model applications

Drug metabolism and toxicology models

Keywords:

xenobiotic metabolism, epoxide detoxification

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ephx1

conditional Knockout mouse

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