Epx conditional Knockout mouse

Target

Gene symbol :

Epx

NCBI gene ID :

13861

Gene full name :

Eosinophil peroxidase

Synonym :

EPO, Epxn

Protein function

Protein name :

Eosinophil peroxidase

Heme peroxidase expressed in eosinophils, generates reactive oxidants involved in parasite defense and inflammation

Expected phenotype

Reduced eosinophil-mediated cytotoxicity, altered inflammatory responses

Human disease relevance

Asthma, allergic diseases, parasitic infections

Model applications

Immunology and inflammation models

Keywords:

eosinophils, peroxidase, type 2 immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Epx

conditional Knockout mouse

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