Target

Gene symbol :  
Erfe
NCBI gene ID :  
227358
Gene full name :  
Erythroferrone
Synonym :  
Fam132b, Myonectin

Protein function

Protein name :  
Erythroferrone
Hormone secreted by erythroblasts that suppresses hepcidin to regulate systemic iron homeostasis

Expected phenotype

Altered iron metabolism and erythropoietic responses

Human disease relevance

Iron overload disorders, anemia

Model applications

Iron metabolism and erythropoiesis models

Keywords:

iron homeostasis, erythropoiesis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Erfe

conditional Knockout mouse

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