Ezh2 conditional Knockout mouse

Target

Gene symbol :

Ezh2

NCBI gene ID :

14056

Gene full name :

Enhancer of zeste 2 polycomb repressive complex 2 subunit

Synonym :

Enx1, KMT6, Lysine methyltransferase 6

Protein function

Protein name :

EZH2

Histone methyltransferase that trimethylates H3K27 to promote gene silencing.

Expected phenotype

Developmental defects, epigenetic dysregulation

Human disease relevance

Cancer driver and stem cell regulator

Model applications

Epigenetics, gene repression, PRC2

Keywords:

H3K27me3, Polycomb, Histone methylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Ezh2

conditional Knockout mouse

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