Target

Gene symbol :  
Fcgbp
NCBI gene ID :  
215384
Gene full name :  
Fc fragment of IgG binding protein
Synonym :  
FcGBP, IgGFcBP

Protein function

Protein name :  
IgG Fc-binding protein
Large secreted mucin-like protein that binds IgG Fc fragments, contributes to mucosal barrier integrity and immune defense

Expected phenotype

Altered mucosal immunity and epithelial barrier function in functional studies

Human disease relevance

Inflammatory bowel disease, cancer

Model applications

Mucosal immunity, epithelial barrier models

Keywords:

mucosal defense, IgG binding, secreted glycoprotein

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
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Fcgbp

conditional Knockout mouse

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