Fcgr3 conditional Knockout mouse

Target

Gene symbol :

Fcgr3

NCBI gene ID :

14131

Gene full name :

Fc gamma receptor III

Synonym :

Cd16

Protein function

Protein name :

Fc gamma receptor III

Low-affinity IgG Fc receptor mediating antibody-dependent cellular cytotoxicity in myeloid and NK cells

Expected phenotype

Impaired antibody-dependent effector functions and immune responses

Human disease relevance

Autoimmune diseases, cancer immunotherapy

Model applications

Immunology, antibody effector function models

Keywords:

ADCC, Fc receptor, innate immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fcgr3

conditional Knockout mouse

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