Ficd conditional Knockout mouse

Target

Gene symbol :

Ficd

NCBI gene ID :

231630

Gene full name :

FIC domain containing

Synonym :

HYPE

Protein function

Protein name :

FICD adenylyltransferase

ER-localized enzyme that AMPylates and de-AMPylates BiP, regulating unfolded protein response

Expected phenotype

Altered ER stress responses and protein folding homeostasis

Human disease relevance

Neurodegeneration, ER stress-related diseases

Model applications

ER stress and proteostasis models

Keywords:

AMPylation, unfolded protein response

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ficd

conditional Knockout mouse

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