Target

Gene symbol :  
Fkbp10
NCBI gene ID :  
14230
Gene full name :  
FK506 binding protein 10
Synonym :  
Fkpbp10

Protein function

Protein name :  
FKBP65
ER-resident peptidyl-prolyl cis-trans isomerase involved in collagen folding and maturation

Expected phenotype

Defective collagen biosynthesis, connective tissue abnormalities

Human disease relevance

Osteogenesis imperfecta, Bruck syndrome

Model applications

Connective tissue and collagen biology models

Keywords:

collagen folding, ER chaperone

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Fkbp10

conditional Knockout mouse

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