Fpgs conditional Knockout mouse

Target

Gene symbol :

Fpgs

NCBI gene ID :

14287

Gene full name :

Folylpolyglutamate synthase

Synonym :

Folylpolyglutamate synthetase

Protein function

Protein name :

Folylpolyglutamate synthetase

Catalyzes polyglutamylation of folates and antifolates, essential for intracellular folate retention

Expected phenotype

Altered folate metabolism, impaired cell proliferation

Human disease relevance

Antifolate drug response, metabolic disorders

Model applications

Folate metabolism and pharmacology models

Keywords:

folate metabolism, antifolate drugs

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fpgs

conditional Knockout mouse

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